CannaronTM is a natural Cannabis medicine for all neuro-degenerative diseases. It helps manage age-related ailments of the brain and the nervous system. It brings relief from wide spectrum of neuropathic conditions, nourishes the neural network, and improves mood and quality of life. A true lifesaver for patients with depression, it has the potential to stimulate, energize and uplift.
This medicine is FREE from chemicals, artificial flavors or sweeteners, sugar, starch, salt, gluten, soy, pesticides and heavy metals
Neuro-degenerative diseases: Neuro-degenerative diseases like Alzheimer's, Parkinson's, MS, Muscle spasms and others are caused due to inflammation. Inflammation causes increased production of beta-amyloid molecules (a sticky type of proteins), which forms amyloid plaques to accumulate between the neurons and creates damage to neurons in brain. THC is found to promote the removal of toxic clumps of amyloid beta protein in the brain and thus protect neurons (1).
Chronic pain: THC (one of CB1 agonists) reduces acute pain through activation of descending spinal serotonin pathways and subsequent activation of 5-HT2A and 5-HT7 receptors in the spinal cord. CBD interacts with pain receptors in the brain to exert pain-relieving and anti-inflammatory effects. A study on patients having neuropathic pain concluded that higher concentration of THC helps in alleviating pain (2).
Mood: A study conducted on 42 participants found that in comparison to placebo, when treated with low dose THC, subject showed significant reduction in both subjective distress and psychosocial stress and improved mood (3).
Depression: Serotonin, produced in brain from neurons, is important for regulating pain, mood, cognition, anxiety & depression. THC inhibits both serotonin-metabolizing MAO(Monoamine oxidase A) activity and serotonin reuptake activity and thus blocks the signal for depression (4).
Quality of life: It is found that cannabis use for cancer pain led to a 64-percent reduction in opioid use, improved quality of life, and caused fewer medication side effects. It also led to participants using fewer medications (5).
MECHANISM OF ACTION
Endocannabinoid system is a collection of neuromodulators (endocannabinoids), their receptors (CB1 & CB2) and signaling pathways in our body. It regulates the body’s physiological system to maintain homeostasis (the state of balance). Phyto-cannabinoids (CBD & THC) bind mainly to CB1 and CB2 receptors and specific enzymes & metabolites to activate the pathways and regulate the symptoms.
This is made using full-spectrum cannabis extract infused in coconut oil. The high grade organic coconut oil boosts the absorption of cannabinoids because it allows easy absorption in the digestive tract and metabolism in liver. Infusion of cannabinoids in coconut oil thus boosts the bioavailability of cannabinoids and helps in breaking down the cannabinoid-coconut oil complex in liver for immediate effect.
- Fawaz A.et al., Neuroinflammatory cytokines induce amyloid beta neurotoxicity through modulating amyloid precursor protein levels/metabolism. BioMed Research International, 2018, vol. 2018, Article ID 3087475, 8 pages. https://doi.org/10.1155/2018/3087475.
- Ware MA. et. al., Smoked cannabis for chronic neuropathic pain: a randomized controlled trial. CMAJ, 2010,182(14):E694-701.
- Childs E. et al. Dose-related effects of delta-9-THC on emotional responses to acute psychosocial stress. Drug Alcohol Depend, 2017, 30: 177:136-144.
- Velenovská M. & Fisar Z., Effect of cannabinoids on platelet serotonin uptake. Addict Biol., 2007, 12(2):158-166.
- Boehnke, K.F. et al., Medical Cannabis Use Is Associated With Decreased Opiate Medication Use in a Retrospective Cross-Sectional Survey of Patients With Chronic Pain. The Journal of Pain,2016, 17(6):739-744.
HPMC veg capsule filled with 125mg Cannabis leaves wholesome extract and organic cold pressed coconut oil. It contains 2% CBD & 4% THC.
*100% plant derived| Cruelty free| Gluten free| Chemical free| Free from synthetic fillers|
SIDE EFFECTS & SAFETY
Cannaron+TM is LIKELY SAFE when taken orally as a prescription medication. Some reported side effects of Cannabis include dry mouth, decrease in blood pressure, increased heartbeat, light-headedness, and drowsiness.
PRECAUTIONS & WARNING
Allergy: DO NOT take this medicine if you are allergic to Cannabis or any of the ingredients contained in this drug.
Pregnancy: Cannaron+TM is not recommended during pregnancy or breast-feeding.
Heart disease: It might increase heartbeat, and fluctuations in blood pressure. Patients suffering from heart diseases should take this under strict Doctor’s guidance and supervision.
Surgery: It might slow down the effect of anesthesia when combined with anesthesia and other medications during and after surgery. Stop taking it at least 2 weeks before a scheduled surgery.
Keep away from Children.
DO NOT drive or operate any machine while under Cannabis medication.
DO NOT take Alcohol while under Cannabis medication.
Taking Cannaron+TM is LIKELY SAFE and can be taken with most drugs.However, it is best to consult your doctor before starting and sharing the list of all medications to find out drug interactions.
Drugs for Sedative medications (Barbiturates & CNS depressants): Taking Cannaron+TM along with sedative medications might cause too much sleepiness. With fluoxetine, it might cause you to feel irritated, nervous, jittery and excited. Doctors call this hypomania.
Drugs for Alcohol de-addiction: Taking Cannaron+TM along with drugs for alcohol de-addiction i.e., Disulfiram can cause agitation, trouble sleeping and irritability.
Drugs that control blood sugar level: No conclusive evidence found for such kind of drug interaction. However it is considerably safe to take with drugs that control blood sugar level.
This drug can also interact with Astemizole, Cisapride, Pimozide & Terfenadine. So it is advisable not to take Cannaron+TM with these drug combinations.
It is advisable to start with low dose as dosage may vary according to disease state and conditions. Dose may also vary from person to person depending on a person’s tolerance level. It is best to follow a physician’s advice to find the right dose.
No specific dose limit has been defined yet. However, mild adverse effects may occur in some at dosage > ~20mg THC, including nausea, postural hypotension, delirium, panic attacks, anxiety, and myoclonic jerking. In case of overdose, get medical help immediately.